DAMAGE to a gene called Bcl10 may trigger many common cancers, say
researchers in Britain.
Martin Dyer and his colleagues at the Institute of Cancer Research in Sutton,
Surrey, found the faulty gene in tissue from lung, colon and testicular tumours
(Cell, vol 96, p 35). The normal Bcl10gene serves as a
鈥渟entinel鈥�, liquidating damaged cells. 鈥淏ut when it鈥檚 damaged, Bcl10
actively turns cells malignant,鈥� says Dyer.