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Randy flies reveal how booze loosens sexual inhibition

Drunkenness in the "Flypub" leads to homosexual behaviour among male flies – and could show how alcohol affects inhibitions

THE sexual preferences of drunk fruit flies will help reveal how alcohol loosens human sexual inhibitions, according to researchers studying the effect of repeated alcohol consumption on the flies’ courtship behaviour.

and colleagues at Pennsylvania State University, University Park, used a chamber dubbed the “Flypub” to observe the influence of alcohol on the sexual behaviour of male Drosophila flies. The researchers through the Flypub’s transparent ceiling.

Male Drosophila will normally only court females, following them and vibrating their wings in a courtship “song” before attempting to copulate. But with repeated doses of alcohol, homosexual courtship became common (PLoS ONE, ). Han has shown that the effect of alcohol on flies’ sexual behaviour depends on the neurotransmitter dopamine, and argues that the flies provide a good model for exploring how alcohol affects human sexual behaviour.

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