杏吧原创

Premature babies may show no sign of pain

Brain scans suggest that some infants born pre-term may not display the usual signs of pain, such as grimacing

Are premature babies suffering in silence? Brain scans suggest that their faces don鈥檛 always show when they are in pain.

Nurses check whether pre-term babies in intensive care are in pain by measuring their heart rate, oxygen levels in their blood and whether they grimace or not 鈥 a series of measurements known as the 鈥減remature infant pain profile鈥. This helps them decide when to give painkillers.

Now Rebeccah Slater and colleagues at , UK, have shown that babies may be in pain without exhibiting any of these signs.

They scanned the brains of prematurely born babies as blood was taken from their heel for routine analysis. In 33 scans on 12 babies, a part of the brain known to register pain in adults 鈥 called the somatosensory cortex 鈥 was activated.

Yet in 10 of these procedures, the babies did not grimace or show outward signs of pain. 鈥淚n some cases infants still had a cortical response without a change in facial expression,鈥 Slater says.

Slater says that pain scores could be improved through further brain studies, and hopes next to see whether pain relief dampens activity in babies鈥 brains.

Journal reference: (DOI: 10.1371/Journal.pmed0050129.sg001)

Topics: pregnancy and birth