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Down’s blood test hits speed bump

An investigation into a company that has claimed rosy results for a non-invasive test for Down's syndrome reveals errors and unsubstantiated assertions

A TEST to reveal whether a fetus has Down’s syndrome from just a drop of its mother’s blood has hit a snag. A panel set up by Sequenom of San Diego, California, to investigate the firm’s seemingly rosy research results has found they contain .

Prenatal Down’s tests typically involve using a needle to draw fluid from the mother’s womb. This carries a small risk of miscarriage. In September 2008, Sequenom said that its test, which dodges this risk as it relies on fetal RNA in the mother’s blood, would be ready by June 2009.

But Sequenom reported on 28 September that the panel found problems with its data. Sequenom sacked five employees and says it cannot predict when its test will be ready, though it stands by the underlying science.

Topics: Genetics